I would let a Nobel Prize winner, Steven Weinberg, a physicist, have the last word.
Lowder's argument represents not only a complete lack of understanding of philosophy, but a complete lack of understanding of the principles underlying science.
Weinberg won the prize in 1977. 25 years later, a physicist friend said to him, "you know science doesn't explain anything it only describes."
Weinberg, horrified, wrote his essay "Does Science Explain Everything? Anything?" And concluded "no."
He tried to redefine "explanation" in order to get out of his horrified state, but failed.
Since then, many writers have patiently tried to explain to scientists why the kind of thing Lowder writes is not just wrong but incoherent
Three suggestions:
Ed Feser, if you can ignore his horrifically sadistic political views (passionate arguments for more and more widespread capital punishment, among others) is actually a very good critic of materialism.
David Bentley Hart's "The Experience of God," is a VERY hard book to read if you're not familiar with theology or philosophy, but the first 100 pages or so has one of the best critiques of materialism I've seen.
Owen Barfield's "Saving the Appearances", in just the first chapter, sums it up so simply even a child would get it (which doesn't mean Weinberg would understand!!)